Tomasz Ciach PhD Eng. Professor
 
Beata Butruk-Raszeja PhD Eng.
 
Magdalena Janczewska MSc Eng.
 
Katarzyna Każmierska MSc Eng.
Kamil Kopeć MSc Eng.
 
Piotr Kowalczyk MSc Eng.
 
Martyna Kucharska PhD Eng.
 
Aleksandra Kuźmińska, MSc Eng.
 
Aleksandra Kulikowska MSc Eng.
 
Ilona Łojszczyk MSc Eng.
 
Aleksandra Mościcka-Studzińska MSc Eng.
 
Rafał Podgórski MSc Eng.
 
Aleksandra Poniatowska MSc Eng.
 
Agata Stefanek MSc Eng.
 
Paulina Trzaskowska MSc Eng.
 
Maciej Trzaskowski MSc Eng.
 

Iga Wasiak MSc Eng.

 
Michał Wojasiński MSc Eng.
 

 

Hydroxyapatite nanoparticles

Recently, nanotechnology is rapid growing science field. In this particular field of knowledge, we are focused on synthesis of nanoparticles and nanofibers by electrohydrodynamic atomization method and by chemical synthesis “bottom-up”.

In our laboratory, we developed the technology of synthesis of hydroxyapatite nanoparticles, under mild reaction conditions, using aqueous environment of lecithin. Hydroxyapatite is a very popular and widely used bone replacing material. It is used as a filling for bone defects, material for bone cell culture or drug carrier. Prepared using lecithin, hydroxyapatite possess increased biocompatibility and may be produced in various forms: spherical nanoparticles, nanoplates, nanorods.

The above graphics schematically shows the formation of hydroxyapatite nanoparticles in the environment of lecithin. In addition, a photograph from scanning electron microscope, which shows a spherical nanoparticles with average size of about 80 nm, and the size distribution of nanoparticles in a sample containing said spherical nanoparticles are shown.

By using the technology of wet precipitation with application of lecithin it is possible not only to prepare nanoparticles of the desired shapes, but also with significantly increased biocompatibility and the ability to form a suspension. The latter feature is particularly advantageous in applications that require the hydroxyapatite to be mixed with other materials, for example polymers.

 

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