Tomasz Ciach PhD Eng. Professor
 
Beata Butruk-Raszeja PhD Eng.
 
Magdalena Janczewska MSc Eng.
 
Katarzyna Każmierska MSc Eng.
Kamil Kopeć MSc Eng.
 
Piotr Kowalczyk MSc Eng.
 
Martyna Kucharska PhD Eng.
 
Aleksandra Kuźmińska, MSc Eng.
 
Aleksandra Kulikowska MSc Eng.
 
Ilona Łojszczyk MSc Eng.
 
Aleksandra Mościcka-Studzińska MSc Eng.
 
Rafał Podgórski MSc Eng.
 
Aleksandra Poniatowska MSc Eng.
 
Agata Stefanek MSc Eng.
 
Paulina Trzaskowska MSc Eng.
 
Maciej Trzaskowski MSc Eng.
 

Iga Wasiak MSc Eng.

 
Michał Wojasiński MSc Eng.
 

 

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SPR effect in microbe detection

SPR effect application in microbe detection

SPR effect

Surface Plasmon Resonance phenomenon (SPR) is nowadays more and more widely used in examination of interactions between analyte and immobilised biomolecule. The SPR effect is dependent on mass changes that occur due to analyte binding which cause changes in refraction index observed as resonance angle shift. Unlike other methods of studying such interactions, SPR technique does not require any additional reagents and enables real-time observations.

When connected with surface modification techniques, microfluidics and suitable software SPR technique offers a unique opportunity to study:

  • kinetics
  • stoichiometry of interactions
  • mechanisms of binding
  • ligand specificity

of every antigen-antibody interaction.

 

Our team's research

Biomedical Engineering Laboratory is currently investigating the possibility to use SPR effect in detection of pathogenic microorganisms. This research is going to find applications in bacterial disease diagnostics and environmental protection.