Tomasz Ciach PhD Eng. Professor
 
Beata Butruk-Raszeja PhD Eng.
 
Magdalena Janczewska MSc Eng.
 
Katarzyna Każmierska MSc Eng.
Kamil Kopeć MSc Eng.
 
Piotr Kowalczyk MSc Eng.
 
Martyna Kucharska PhD Eng.
 
Aleksandra Kuźmińska, MSc Eng.
 
Aleksandra Kulikowska MSc Eng.
 
Ilona Łojszczyk MSc Eng.
 
Aleksandra Mościcka-Studzińska MSc Eng.
 
Rafał Podgórski MSc Eng.
 
Aleksandra Poniatowska MSc Eng.
 
Agata Stefanek MSc Eng.
 
Paulina Trzaskowska MSc Eng.
 
Maciej Trzaskowski MSc Eng.
 

Iga Wasiak MSc Eng.

 
Michał Wojasiński MSc Eng.
 

 

Home arrow Projects arrow Coatings for medical use arrow Hemocompatible biomimetic surfaces
Hemocompatible biomimetic surfaces

Molecules presenting phosphorylcholine groups have been proven to significantly increase material hemocompatibility. In the presented modification method we applied soybean-derived phosphatidylcholine, which turn out to be a promising alternative for its synthetic analogues. We also propose a new standard for testing material’s hemocompatibility, which involve contact with human blood under dynamic conditions. This method reflects the exact conditions of arterial flow. The modified materials incubated with human plasma exhibited high repellency toward fibrinogen and platelets. The analysis of blood-materials interactions performed under arterial-flow simulated conditions confirmed excellent hemocompatibility of the coating.

Fig.1: Phosphatidylcholine coated polyurethanes exhibited high platelet repelency.

 

Contact person:

Beata Butruk (e-mail)

More info:

Papers available on ResearchGate.

 
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