Tomasz Ciach PhD Eng. Professor
 
Beata Butruk-Raszeja PhD Eng.
 
Magdalena Janczewska MSc Eng.
 
Katarzyna Każmierska MSc Eng.
Kamil Kopeć MSc Eng.
 
Piotr Kowalczyk MSc Eng.
 
Martyna Kucharska PhD Eng.
 
Aleksandra Kuźmińska, MSc Eng.
 
Aleksandra Kulikowska MSc Eng.
 
Ilona Łojszczyk MSc Eng.
 
Aleksandra Mościcka-Studzińska MSc Eng.
 
Rafał Podgórski MSc Eng.
 
Aleksandra Poniatowska MSc Eng.
 
Agata Stefanek MSc Eng.
 
Paulina Trzaskowska MSc Eng.
 
Maciej Trzaskowski MSc Eng.
 

Iga Wasiak MSc Eng.

 
Michał Wojasiński MSc Eng.
 

 

Home arrow News arrow Project CardioMat
Project CardioMat

Our team is working on the bioactive surfaces to promote surface endothelialization (colonization of biomaterial with endothelial cells). Under physiological conditions the process of blood clotting is controlled by endothelial cells. These cells constantly and actively prevent thrombosis by releasing a number of substances. Synthetic materials are not able to release certain substances due to limited capacity. Thus, the most promising strategy to fabricate non-thrombogenic materials is covering the implant surface with a layer of endothelial cells. This approach seems to be the most close to ideal, leading to hybrid implants - artificial devices coated with a layer of living cells permanently connected to the implant and actively prevent platelet activation and transplant rejection.

The proposed modification process leading to formation of bioactive, peptide-based coating

 

The bioactive coating enhances adhesion of endothelial cells and improves biocompatibility of the material

 

Endothelial cells growing on non-modified polymer (PU) and peptide-modified polymer (PU-REDV)

 

Contact person:

dr Beata Butruk-Raszeja (send e-mail)

 

 

Research funded from Norway Grants in the Polish-Norwegian Research Programme operated by the National Centre for Research and Development.

 
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