Tomasz Ciach PhD Eng. Professor
Beata Butruk-Raszeja PhD Eng.
Magdalena Janczewska MSc Eng.
Katarzyna Każmierska MSc Eng.
Kamil Kopeć MSc Eng.
Piotr Kowalczyk MSc Eng.
Martyna Kucharska PhD Eng.
Aleksandra Kuźmińska, MSc Eng.
Aleksandra Kulikowska MSc Eng.
Ilona Łojszczyk MSc Eng.
Aleksandra Mościcka-Studzińska MSc Eng.
Rafał Podgórski MSc Eng.
Aleksandra Poniatowska MSc Eng.
Agata Stefanek MSc Eng.
Paulina Trzaskowska MSc Eng.
Maciej Trzaskowski MSc Eng.

Iga Wasiak MSc Eng.

Michał Wojasiński MSc Eng.


Home arrow Projects arrow Tissue engineering arrow Bone implants - Scaffolds
Bone implants - Scaffolds

The subject of our recent research became bone implants, called scaffolds. Medicine knows many cases, where traumatic accidents, bone cancer resection and fractures as a consequence of osteoporosis lead to bone tissue loss. In all these cases it is possible to restore damaged bone using synthetic polymer matrix and human cells. Tissue engineering, focused on tissue regeneration, helps medicine in such situation. Having porous scaffold with controllable shape, suitable and predictable pore size, made of degradable polymers with controllable degradation rate and non toxic degradation products, damaged tissue can be reconstructed. Regeneration process is very complex and for that reason needs the knowledge of many fields of science e.g. engineering, material science, cell biology and many others. Despite the fact many scientists have been looking for the right material and method for making scaffold, many problems are still not solved. Therefore, bone scaffold became the purpose of our research.

Bone scaffolds, we work on, are generally made from chitosan. It is polysaccharide that is naturally found in some of the fungi cell walls. Commercially, it is produced by deacetylation of chitin, the structural element of crustaceans shells. Because of its biocompatibility and hydrophilic surface that promotes cell adhesion, chitosan is the promising material for bone tissue engineering application. Although the material we concentrate on is chitosan, we also use another polymers such as: polycaprolactone, polylactic acid in their pure form as well as in composition with ceramics (β-TCP, hydroxyapatite) and collagen . Porous materials are fabricated by Rapid Prototyping technology, agglomeration of polymer/composite microgranules, freeze drying and foaming.

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