Tomasz Ciach PhD Eng. Professor
Beata Butruk-Raszeja PhD Eng.
Magdalena Janczewska MSc Eng.
Katarzyna Każmierska MSc Eng.
Kamil Kopeć MSc Eng.
Piotr Kowalczyk MSc Eng.
Martyna Kucharska PhD Eng.
Aleksandra Kuźmińska, MSc Eng.
Aleksandra Kulikowska MSc Eng.
Ilona Łojszczyk MSc Eng.
Aleksandra Mościcka-Studzińska MSc Eng.
Rafał Podgórski MSc Eng.
Aleksandra Poniatowska MSc Eng.
Agata Stefanek MSc Eng.
Paulina Trzaskowska MSc Eng.
Maciej Trzaskowski MSc Eng.

Iga Wasiak MSc Eng.

Michał Wojasiński MSc Eng.


Home arrow Projects arrow Coatings for medical use arrow Polymers with antibacterial action
Polymers with antibacterial action

Polymeric biomaterial, defined as any natural or synthetic substance interfacing with living tissue at some stage of patient’s therapy, have to fill rigorous conditions prior to use in humans

Urethral catheters are one of the most widely used polymeric medical devices. In our work we focused on the PVC Nelaton type catheters with hydrogel coatings (Galmed) and silicone Foley catheters. The other types of medical devices modificated in our lab were tracheotomy silicone “T-tubes” and sutures (absorbable and non-absorbable).The idea of modification was quite simple: to impregnate ready-made medical devices (with or without additional hydrogelly coating) with antimicrobial agents (Triclosane, parabens, iod and others; diffused in bulk or complexed by outer layer). This approach can guarantee rapid and strong protection against infections during implementation of the device and from 24h to more than 10 days after. Hydrogel coated polymers, even without antibacterial substances, can slow down bacterial colonization of the surface through lower adherence of hydrophobic species. We have tested an antimicrobial action of prepared tubes by zone measurements of E. coli inhibited grow around fragments of catheters immersed in agar onto Petri dish. We also performed the studies of drug release kinetics to the PBS buffer.

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